Yeah I've played through about 20% of Four Swords Adventures with a PC running Dolphin and 3 emulated VBA-M instances, a TV, and 3 monitors, and 3 game controllers. Once up and running it's a great experience, but requires a lot of planning and setup (just like running on real hardware).

It's a shame so few people get to play that kind of game. It's a very social experience and exactly what the Wii U was intended for.