Mirtazapine will do that to a bit of an extreme. Escitalopram didn't, at least for me, in some ways it made it slightly more difficult to sleep. This is in my body, so everyone's mileage may vary. I found the massive drowsiness of mirtazapine so difficult to deal with that I ended up preferring the frustrating sexual side-effects that escitalopram has (and found it more effective for my depression anyway).

Lately, the buprenorphine injection I get once a month is all the antidepressant I need. Still has side-effects, but these are ones I'm very used to at least.