My wife has a chronic, expensive, difficult to manage, and unpredictable health condition. Having to leave her to be in an office when I’ve been doing great work from home is a show stopper for me. And I’m always upfront about that with employers, I get some companies have an on-prem mentality and I’m respectful of that. But it doesn’t work for me, so I’m not trying to waste their time or mine. And my current employer while I regularly complain about the logistics of working in a gigantic enterprise has been very respectful of our situation and hasn’t once ever made me feel like I’m slowing down or underperforming because of it. So long as I keep making the company money and they keep paying me, neither of us cares where the other sits.