Why would the story be different than SPAs? The screenreaders read final html in the browser. It shouldn't matter if comes from server rendered template OR javascript template rendered on the client.
Seems like it depends on how you code the html/templates not how they are rendered?
SPAs very often have terrible accessibility. I think it's important for frameworks that help people build interactive applications (SPA or otherwise) to provide the best possible defaults, plus guidance as to how to use them to build accessible interfaces.
Seems like it depends on how you code the html/templates not how they are rendered?