Not if you’re a slow metabolizer. 15% of the population.
CYP1A2
Increased heart attack risk: A 2006 study found that slow metabolizers who drank four or more cups of coffee per day had a 64% increased risk of a nonfatal myocardial infarction (heart attack) compared to those drinking less than one cup daily. The risk was even higher for slow metabolizers under age 50, who experienced more than four times the risk
No increased risk for fast metabolizers: In the same study, fast metabolizers did not experience an increased risk of heart attack, even with high coffee consumption.
CYP1A2
Increased heart attack risk: A 2006 study found that slow metabolizers who drank four or more cups of coffee per day had a 64% increased risk of a nonfatal myocardial infarction (heart attack) compared to those drinking less than one cup daily. The risk was even higher for slow metabolizers under age 50, who experienced more than four times the risk
No increased risk for fast metabolizers: In the same study, fast metabolizers did not experience an increased risk of heart attack, even with high coffee consumption.