Perhaps, but AFAIK similar things show up in other metabolically "different" animals - sharks, naked mole rats - whereas rodents adapted to a "run hot and fast" kind of a lifeplan seem to be especially prone.
We know that the body has cancer suppressor mechanisms, because when they fail (due to HIV or genetic mutations) people suffer higher rates of the disease. So it's reasonable to guess that evolution has chosen not to dial them up further.
It feels like the immune/inflammatory system is something we understand about as well as the brain, which is to say pretty good at a gross anatomical level, and also at the fine molecular level, but with a heck of a lot of complex system dynamics in between remaining to be mapped out.
We know that the body has cancer suppressor mechanisms, because when they fail (due to HIV or genetic mutations) people suffer higher rates of the disease. So it's reasonable to guess that evolution has chosen not to dial them up further.
It feels like the immune/inflammatory system is something we understand about as well as the brain, which is to say pretty good at a gross anatomical level, and also at the fine molecular level, but with a heck of a lot of complex system dynamics in between remaining to be mapped out.